Melissa & Rex: Let It Go! provides a rare glimpse into the often-dreamed-of lives of musicians on the road. The concert was filmed in April 2006 before of a sold-out audience at the Sanderson in Brantford, ON. It showcases the pair’s most-loved hits including “Alive”, “Let it Go” and “Run”. In addition to the Brantford performance, Melissa & Rex: Let It Go! features footage from concerts at St. John’s Mile One Stadium in Goudie’s home province of Newfoundland and Labrador, in O’Neil’s hometown of Calgary as well as other venues across Canada.